Material Safety Data Sheet (MSDS)
n-hexane
Hexane MSDS Material Safety Data Sheet
Part 1: Chemicals and Corporate Logo
Common name or trade name of the chemical: Hexane
English name of the chemical: n-hexane;
Company Name: Chuzhou Runda Solvent Co., Ltd
Address: Chahe Development Zone, Lai'an County, Chuzhou City
Tel: 0550-5962799
Email address: sales@rundachem.com
Postal code: 239236
Technical specification code: RD-016
Effective Date: October 1, 2010
Enterprise emergency contact: (+86) (0550) (5962333)
Fax number: (+86) (0550) (5962782)
National emergency hotline: 0532-8388-9090
Molecular formula: C6H14
Part II: Composition/Ingredient Information
mixture
Harmful substance: n-hexane
Concentration: 60%

CAS NO： 110-54-3
Part III: Physicochemical Constants of Substances
English name: n-hexane
Alias: Hexane
Molecular formula: C6H14
Melting point: -95.6℃
Boiling point: 68.7℃
Density: Relative density (water=1) 0.66;
Vapor pressure: -25.5℃ (Vapor pressure: 13.33kPa/15.8℃)
Solubility: Insoluble in water, soluble in most organic solvents such as ethanol and ether
Stability: Stable
Appearance and Characteristics: Colorless liquid with a faint specific odor
Danger sign: 7 (low flash point flammable liquid)
Purpose:
Used in organic synthesis, as a solvent, chemical reagent, paint thinner, medium for polymerization reactions, etc
Part IV: Impact on the Environment
1. Health hazards
Route of entry: inhalation, ingestion, percutaneous absorption.
Health hazards: This product has anesthetic and irritating effects. Prolonged exposure may cause peripheral neuritis.
Acute poisoning: Inhaling high concentrations of this product can cause headache, dizziness, nausea, ataxia, etc. In severe cases, it can lead to loss of consciousness or even death. It is irritating to the eyes and upper respiratory tract.
Chronic poisoning: Long-term exposure leads to symptoms such as headache, dizziness, fatigue, and decreased appetite. Subsequently, the distal ends of the limbs gradually develop into sensory abnormalities, numbness, and decreased sensitivity to touch, pain, vibration, and position, especially in the lower limbs, with less involvement in the upper limbs. Further progression leads to lower limb weakness, muscle pain, muscle atrophy, and movement disorders. Nerve-electromyography examination shows slow conduction velocities of sensory and motor nerves.
II. Toxicological Information and Environmental Behavior
Toxicity: It belongs to the low toxicity category.
Acute toxicity: LD50 28710 mg/kg (oral administration in rats); inhalation in humans at 12.5 g/m3 may cause mild intoxication, headache, nausea, and irritation to the eyes and respiratory system.
Subacute and chronic toxicity: Rats inhaled 2.76g/m3/day for 143 days, showing reduced nocturnal activity, mild abnormal response in the reticuloendothelial system, degenerative changes in the myelin sheath of peripheral nerves, mild changes in axons, and mild atrophy of gastrocnemius muscle fibers.
Hazardous characteristics: Highly flammable. Its vapor can form an explosive mixture with air. It is extremely prone to combustion and explosion in the presence of open flames or high heat. It reacts violently when in contact with oxidizers, even causing combustion. In a fire scene, heated containers pose an explosion hazard. Its vapor is heavier than air and can spread to considerable distances in lower areas, igniting backdrafts when encountering open flames.
Combustion (decomposition) products: carbon monoxide, carbon dioxide.
Part V: On-site Emergency Monitoring Methods
Gas detection tube method
Gas velocity measuring tube (product of Beijing Labor Protection Institute, product of German Draeger Company)
4. Laboratory monitoring methods:
Gas Chromatography, "Methods for Analysis of Additives in Foods", translated by Ma Jiaxiang et al
Gas Chromatography, "Determination Methods of Harmful Substances in Air" (Second Edition), edited by Hang Shiping
5. Environmental standards:
Maximum allowable concentration of harmful substances in the air of workshops in the former Soviet Union: 300mg/m3
The maximum allowable concentration in ambient air in the former Soviet Union (1978) was 60mg/m3 (single value)
6. Emergency response and disposal methods:
Part VI: Emergency Response for Leaks
Evacuate personnel from the contaminated area to a safe area quickly, and isolate them, strictly restricting their entry and exit. Cut off sources of ignition. It is recommended that emergency personnel wear self-contained positive pressure breathing apparatus and wear firefighting protective clothing. Try to cut off the source of leakage. Prevent entry into restricted spaces such as sewers and flood discharge channels. Small leakage: Use sand or other non-combustible materials to adsorb or absorb. Alternatively, use a lotion made from non-combustible dispersant to scrub, and dilute the lotion before discharging it into the wastewater system. Large leakage: Build a containment dike or dig a pit for containment; cover with foam to reduce vapor hazards. Use an explosion-proof pump to transfer the material to a tanker or a dedicated collector for recycling or transportation to a waste disposal site.
Part VII: Protective Measures
Respiratory protection: When the concentration in the air exceeds the standard, wear a self-priming filter type gas mask (half-face mask).
Eye protection: Wear chemical safety goggles when necessary.
Body protection: Wear anti-static work clothing.
Hand protection: Wear benzene-resistant and oil-resistant gloves.
Others: Smoking is strictly prohibited on the job site. Avoid long-term repeated exposure.
Part 8: First Aid Measures
Skin contact: Remove contaminated clothing and thoroughly wash the skin with soap water and clean water.
Eye contact: Lift the eyelid and rinse with running clean water or saline solution. Seek medical attention.
Inhalation: Quickly leave the scene and move to a place with fresh air. Keep the respiratory tract clear. If breathing is difficult, administer oxygen. If breathing stops, immediately perform artificial respiration and seek medical attention.
Ingestion: Drink plenty of warm water, induce vomiting, and seek medical attention.
Fire extinguishing method: Spray water to cool down the container, and if possible, move the container to an open area. If the container in the fire scene has discolored or sounds have been emitted from the safety pressure relief device, it must be evacuated immediately.
Fire extinguishing agents: foam, dry powder, carbon dioxide, sand. Water is ineffective for extinguishing the fire.